perineural invasion
Synonyms: perineural involvement
Abbreviations: PNI
Definition: This may be part of the pathology report to help grade the cancer. It refers to the growth of a tumor along the nerve (perineural) branches of the prostate gland. This path may act as a highway, allowing the tumor to escape outside the confines of the prostatic capsule. It does not mean the cancer has spread to the cavernous nerves in the penis.
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